China's imported CNC machine tools show volume increase and decrease in the first quarter

The data shows that in the first quarter of 2017, the import value of China's CNC machine tools reached 54.214 million U.S. dollars, and the cumulative amount decreased by 27.4% year-on-year;

Data show that in the first quarter of 2017, China’s CNC machine tool imports amounted to USD 54.214 million, and the accumulated amount decreased by 27.4% year-on-year. In terms of quantity, the number of imported CNC machine tools was 2,617 units in the first quarter, a year-on-year increase of 0.2%, and imports of CNC machine tools increased. The price decreases.

Compared to developed countries in Europe and America that have entered the era of post-industrialization and relatively constant demand for machine tools, China's industrialization process is not over yet. The rise of automobiles and electronic consumption and the demand for machine substitutions have made China's machine tool market potential reachable. It is the fancy business opportunity in the Chinese machine tool market that many world-renowned machine tool manufacturers have entered the Chinese market one after another. In particular, since the market situation improved last year, it has even accelerated the investment and layout. China's machine tool market has shown significant characteristics of intensified international competition.

In recent years, despite China's machine tool industry breaking through foreign technology blockade, through independent innovation, successfully developed a number of high-precision, high-speed, high-efficiency CNC machine tools, and improved the manufacturing capabilities of key equipment required by key industries in the national economy. But at the same time, we must also clearly understand that in the function, performance and reliability of some high-end CNC machine tools, China still has a big gap with the international advanced level.

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China's first domestically produced main bearing remanufacturing shield successfully originated

On May 1, China's first domestically produced main bearing remanufacturing shield CT006H was successfully launched on the left line of Ziyun Road Station, the second-line project of the Hefei Rail Transit Line No. 3, which was built by the China Railway Tunnel Group.

On May 1st, China's first domestically produced main bearing remanufacturing shield CT006H was successfully launched on the left lane of Ziyun Road Station, the second-line project of the Hefei Rail Transit Line No. 3, which was built by the China Railway Tunnel Group, marking China's breakthrough in the construction of the shield's main bearing. After the bottleneck of the independent technology was developed, the underground excavation task was performed for the first time.

This shield machine is an earth pressure balance shield machine that is better organized to remanufacture the Hefei formation. China Railway Tunnel Group adopts the “Scientific Research + Production Order” model in a pioneering way. Under the leadership of the scientific research team of the National Key Laboratory of Shield Tunneling and Excavation Technology of China Railway Tunnel, it cooperates with Luoyang LYC Bearing Co., Ltd. to form a raw material design, etc. With 6 independent intellectual property rights and a number of special standards, the localization of shield main bearings has been successfully achieved.

In order to build a new tool for tunnel construction and breakthrough in the self-developed bottleneck of the shield main bearing, the R&D team of the China Railway Tunnel Group has continuously increased the research efforts on the main bearing of the shield machine. On November 26, 2016, CT006H, China's first domestically produced main bearing remanufactured shield machine, went offline in Hefei and began to be assembled on January 5, 2017. During the period, China Railway Tunnel Group organized many personnel such as shield experts, equipment managers, skilled workers, etc., proceeding from aspects of program demonstration, transportation and assembly, equipment debugging, etc., and was meticulous, accurate, and accurate in each step of the construction process. It ensures the normal operation of various parts such as the shield body, cutter head drive, segment assembly machine, soil discharging mechanism, and electrical system, and has passed the acceptance of the shield node.

The total length of the Hefei Metro Line 3 is 37.2 kilometers. The line passes through the Feixi County and the Hefei Economic Development Zone, the Administrative New Area, the Laoshan District, the Xiangyang District, the Yaohai District and the Xinzhan District. After the completion of the line, it will further improve the Hefei rail transit network, better serve the economic development of Hefei, and increase the happiness index of Hefei citizens' traffic travel.

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Raising the Cyber ​​Security Standard for Driverless Cars and Building New Advantages in the UK

With the rapid development of driverless technology and car networking, automotive network security is becoming a serious topic that must be faced.

With the rapid development of driverless technology and car networking, car network security is becoming a serious topic that has to be faced. Recently, the British government has funded the 5×StarS alliance to improve the cyber security standards of the autonomous automotive industry.

The 5×StarS Alliance has just received funding from the British government to improve the network security standards of the autonomous automotive industry. The alliance consists of UK vehicle development engineering consultancy HORIBAMIRA, construction machinery technology company Ricardo, ItatchamResearch, which specializes in providing data for the UK automobile insurance industry, and technology company Roke and Axillium Research, which integrates research, testing, and consulting.

Together, they will participate in the "Protect Automotive Cyber ​​Security" program as part of the government's efforts to make the UK a global hub for the development, testing, and commercialization of autonomous vehicles. The Secretary of Commerce and Energy, Greg Clarke, said: "The competition for the development of networking and driverless vehicles is intensifying. As a government, we are determined to build our own advantages and ensure that Britain is at the forefront of the revolution."

Specifically, the alliance will develop an industry safety assurance standard to ensure that all components and systems used in vehicles are tested and comply with relevant cybersecurity standards. The standard is a star rating system for the security of driverless car cyber attacks, similar to the European NCAP (European New Car Collision Test) rating for car crash safety. Therefore, this is good news for the connected car industry, consumers and insurance companies, although it is not yet clear which safety standards the alliance will develop.

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How many red wines are suitable for drinking every day?

Many people think that wine is red wine. In fact, the relationship is reversed. Red wine is red wine, so red wine is a kind of wine and it is a fruit wine that is fermented after being naturally fermented. According to the color, there are white wines and pink wines besides red wines. Red wines can be divided into sweet red wines, semi-sweet red wines, semi-dry red wines and dry red wines.

Now people can often see red wine in their daily lives, like red wine and steak, and red wine is usually served with red meat. The composition of red wine is relatively simple, more than 80% is grape juice, 10%-30% of the components are the alcohol produced by the fermentation of the sugar in the grapes, and the rest are like tartaric acid, tannic acid, minerals, pectin and other 1000 species. Substances, but the quality of red wine is to see whether these substances can balance, so that the taste of red wine glycol.

Red wine is rich in vitamins, such as vitamin B1, vitamin B2, vitamin B5, vitamin B6, vitamin B12, vitamin C, vitamin E, also contains 24 kinds of amino acids, and contains 8 kinds of essential amino acids, red wine also contains pantothenic acid 1 Milligrams per liter, inositol 300-500 mg per liter, choline, polyphenols, resveratrol 1 mcg per liter, minerals (calcium, iron, phosphorus, sodium, magnesium, copper, potassium, selenium, manganese, cobalt , iodine, sulfur, zinc, etc.

From the nutritional content of red wine can be seen, the nutrition of red wine and its rich, then the effect of drinking wine is certainly a lot, here's a brief introduction to the efficacy of red wine.

1. Assist in digestion

Red wine was chosen as a table wine, because red wine stimulates the secretion of gastric juice in the stomach, which helps digestion, and the tannin in red wine can promote smooth muscle contraction in the intestine.

2. Anti-aging

Red wine contains a variety of antioxidants, such as vitamin C, vitamin E, tannins, flavonoids, phenols, antioxidants can clear the body's free radicals, and thus play an anti-aging role.

3. Lower cholesterol

Red wine can increase high-density lipoprotein in human blood, and high-density lipoprotein can promote the metabolism of cholesterol, thereby reducing the content of cholesterol in blood, and red wine also contains a polyphenolic substance that can inhibit platelet aggregation and thus prevent thrombosis. produce.

4. Prevent fatty liver

Red wine contains inositol which can promote the metabolism of fat in human liver tissue and other tissues to prevent fatty liver.

5. Beauty

Red wine has always been considered to be able to cosmetology, and the fact is indeed the case, as many businesses have launched a red wine mask, because the low concentration of acid in red wine can clean the skin and also anti-wrinkle. If you drink wine in the right quantity every day, you can also enjoy beauty and beauty.

6. Nourishing the body

Red wine is rich in nutrients. As already mentioned above, it is not reported one by one. Therefore, proper drinking of red wine is beneficial to health. Attention should be given to the right amount. Excessive alcoholism can cause injury. Drink is good for the wine, but if you drink it wrong, then what is the amount of red wine per day?

According to the red wine with 12% alcohol content, adult males drink 300-400 ml a day and females 250-350 ml. This amount is best for 3 to 4 days a week, and if you want to drink every day, then drink red wine. The amount will be reduced to 50-100 ml, and do not drink on an empty stomach. Although the wine is good, but the wine is also wine, not an empty stomach to drink. As for the time of drinking red wine, generally 7 to 9 o'clock in the evening after dinner is best. At this time, the activity of ethanol transaminase in the human body is relatively high, and the alcohol will be decomposed at the fastest speed. It is said that drinking red wine before going to bed helps sleep.

Some people like to add sprites in red wine to improve the sour taste of red wine, but this will make you eat too much sugar, and adding sprite will destroy the original nutrition of red wine. Others like to add ice cubes to red wine. This will dilute the taste of the red wine. Generally, red wine is placed in the ice bucket to make the red wine reach the optimal drinking temperature of 14-18 degrees Celsius.

Intermediates of Cladribine, Carvedilol, Lurasidone, olmesartan, Risedronate Sodium, Atazanavir, Saxagliptin, Dabigatran,Dapoxetine,Cefixime,Ceftaroline fosamil and etc.

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MAIN API PRODUCTS USP/BP

PRODUCT NAME	CAS NUMBER	SPEVIFICATION
Azithromycin	117772-70-0	BEP
Cefpirome Sulphate sterile	84957-29-9	USP JP16
Ceftriaxone Sodium (Sterile)	104376-79-6	USP31
Cefotaxime	64485-93-4	USP30
Ciprofloxacin HCL	85721-33-1	USP/BP
Gentamicin sulphate	1405-41-0	BP
Levofloxacin	100986-85-4	USP27
Lincomycin Hydrochloride	859-18-7	EP6.0
Moxifloxacin Hydrochloride	186826-86-8	USP31
Tigecycline	220620-09-7	USP
Linezolid	165800-03-3	EP
Dexamethasone	50-02-2	USP/BP/EP
Methylprednisolone	83-43-2	USP/BP/EP
Dexketoprofen trometamol	156604-79-4	BP2008
Ibuprofen	15687-27-1	BP
Metamizol	68-89-3	DAB
Sulindac	38194-50-2	USP/BP/EP
Naproxcinod	163133-43-5	USP28
Tripelennamine Hydrochloride	154-69-8	USP28
Itraconazole	84625-61-6	USP/BP
Cytarabine	147-94-4	USP31
Leucovorin Calcium	1492-18-8	USP32
Valsartan	137862-53-4	USP30
Telmisartan	144701-48-4	USP31
Rosuvastatin Calcium	147098-20-2	USP/BP
Pitavastatin Calcium	147526-32-7	USP/BP
Fluvastatin	93957-54-1	USP31
Vinpocetine	42971-09-5	EP6.0
Atazanavir	198904-31-3	BP
Rosiglitazone	122320-73-4	USP30
Esomeprazole Magnesium	161973-10-0	USP/BP
Topiramate	97240-79-4	USP31
Fexofenadine HCl	153439-40-8	Inhouse
Bosentan	147536-97-8	Inhouse
D-Cysteine	921-01-7	Inhouse
D-Phenylalanine	673-06-3	Inhouse
Linagliptin	668270-12-0	Inhouse
Rivaroxaban	366789-02-8	USP
Saxagliptin	361442-04-8	USP
Vildagliptin	274901-16-5	USP

Major Pharmaceutical Intermediates

Items Descripation	Structure	Application
MICA ESTER CAS No: 246035-38-1 Purity: ≥98%		For Cefixime
EHATA CAS No: 64485-82-1 Purity: ≥98%		For Ceftazidine
2-Chloroadenine CAS No: 1839-18-5		For Cladribine, Fludarabine et al
Bicyclo(2,2,1)Heptane-2,3-di-exo-carboximide CAS No: 14805o-29-9		For Lurasidne
(R,R)-1,2-Bis(methanesulfonyloxy methyl)Cyclohexane CAS No: 186204-35-3		For Lurasidone
3-(Piperazin-1-yl)benzol[d] isothiazole CAS No: 87691-87-0		For Lurasidone
Trityl olmesartan CAS No: 144690-92-6 Purity: ≥98%		For olmesartan
3-Acetyl Pyridine CAS No: 350-03-8		For Risedronate Sodium
3-(AceticAcid)pyridine HCL CAS No: 6419-36-9		For Risedronate Sodium
Risedronic Acid CAS No: 105462-24-6		For Risedronate Sodium
3-Hydroxy-1-adamantyl-D-Glycine CAS No: 709031-29-8		For Saxagliptin
(1s,3s,5s)-3-(aminocarbonyl)-2-azabicyclo(3,1,0) hexane-2-carboxylic acid tert-butyl ester CAS No: 361440-67-7		For Saxagliptin
(S)-N-Boc-3- hydroxy-adamantylglycine CAS No: 361442-00-4		For Saxagliptin
2-Azabicyclo[3.1.0] hexane-3-carbonitrile, (1s,3s,5s)- CAS No: 866083-42-3		For Saxagliptin
Ethyl 3-(pyridin-2-ylamino) propanoate CAS No: 103041-38-9		For Dabigatran
N-(4-Cyanophenyl) glycine CAS No: 42288-26-6		For Dabigatran
4-methylamino-3-nitrobenzoic Acid CAS No: 41263-74-5		For Dabigatran
S-3-Amino-3-phenylpropanoic acid ethyl ester HCL CAS No: 167834-24-4		For Dapoxetine
(S)-3-Amino-3-Phemylpropan -1-ol CAS No: 82769-76-4		For Dapoxetine
(S)-3-Dimethylamino-3-Phemylpropanol CAS No: 82769-75-3		For Dapoxetine
4-{4-[4-(hydroxydiphenylmethyl)-1-piperidinyl]-1-butynil}-α,α-dimethyl benzene acetic acid CAS No: 832088-68-3		For Fexofenadine HCl
Methyl 2-(4-(4-chlorobutanoyl)phenyl)-2-methylpropanoate CAS No:154477-54-0		For Fexofenadine HCl
5-Bromo-2-chlorophenyl)(4-ethoxyphenyl)methanone CAS No 461432-22-4		For Dapagliflozin
4-(5-Bromo-2-chlorobenzyl)phenyl ethyl ether CAS No :461432-23-5		For Dapagliflozin

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Experts uncover the truth behind the joint cancer between husband and wife

64-year-old teacher Huo had unfortunately got advanced lung cancer. He had surgery and radiotherapy and chemotherapy in the hospital. Since Mr. Huo's hospitalization began, his wife has been escorting his beside him every day, taking good care of him, and washing his face with tears all the time. He is extremely sad. Six months later, Mr. Huo’s wife was also found to have suffered from lung cancer. The teacher's son asked his doctor, "My father is suffering from lung cancer. It has nothing to do with his 40-year history of smoking. But my mother doesn't smoke or drink. How can she get lung cancer?"

Doctors explained that “husband cancer” like Huo’s has been a phenomenon that has gradually become of concern to the medical community in recent years. This may be because husbands and wives have lived together for a long time because they share the same way of life and they share the same Under carcinogenic risk factors, carcinogenic factors often endanger both parties in the same way and may induce the same or different cancers. When her husband smokes, his wife will suffer from passive smoking; eating at the same table, bad eating habits will also harm both parties; cohabitation, environmental carcinogenic factors will be harmful to both parties. Gastrointestinal cancer is very common in couple cancers. It is more common in families who like to eat spicy foods and pickle foods. In addition, negative psychological factors may also be the cause of "marital cancer." If one of the spouses is suffering from cancer, the other is bound to be in anxious and anxious. The mental and physical pressure will increase dramatically, the immune function will decline sharply, and the potential carcinogenic factors in the body will soon become active. The chance of suffering from cancer is greatly increased.

In fact, most preventable cancers are related to human behavior. If people choose a healthy lifestyle, many cancers can be prevented. To communicate with others, to maintain a good mood, not to smoke, not to drink too much, to keep exercising, to eat less meat, to fry, to mold, pickle and smoke food, to control weight, etc. can reduce the risk of cancer. (Zhao Chenghui)

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New Algae Lycopene Content Will Be More Than 1500 Times More Than Tomato

A new research result from Nankai University has successfully obtained a large number of high-purity “plant gold” lycopene from natural seaweed plants. The research results have been selected into the "Special Scientific Research Project of Marine Public Welfare Industries" of the State Oceanic Administration.

Lycopene, known as "plant gold," belongs to carotenoids and is one of the strongest antioxidants found in nature today. The study found that it has preventive and therapeutic effects on cancers such as prostate cancer, breast cancer, and pancreatic cancer, vascular sclerosis, and coronary heart disease. In addition, it is also selected as one of the top ten health food additives for modern people.

Lycopene has a broad market prospect. At present, the method for obtaining lycopene is mainly extracted from tomatoes, and chemically synthesized and fermented by microorganisms. Each of the three methods has its own drawbacks. The content of tomato raw materials is too low and the production cost is high. The chemical synthesis products not only have poor physiological functions, but also can not show their advantages in the market because of people's concerns about their toxic and side effects; The supply of synthetic precursors is limited, and there is no substantial breakthrough in production efficiency.

Nankai University will adopt a gene knockout technique to redesign the metabolic pathway of Dunaliella salina carotenoids to obtain a new D. salina variety with a lycopene content of more than 6% dry weight. It is estimated that the unit content of lycopene in this cultivar is 1500 times that of tomato and 100 times that of microbial fermentation bacteria, which is much higher than the level of similar research at home and abroad.

The head of the project team, Professor Chen Defu of the School of Life Sciences of Nankai University, said: "D. salina is a salt-producing, cell-free single-celled green algae, and the highest content of beta-carotene, if it is artificially disrupted. The function of the intracellular lycopene β-cyclase gene allows lycopene to no longer be metabolized into β-carotene, which is accumulated and stored in cells, and the intracellular lycopene content will increase dramatically.”

Gene knockout technology is a genetic engineering technology developed in the late 1980s and won the Nobel Prize in Physiology and Medicine in 2007. It has fixed and quantified the genome at the DNA level in a certain way to achieve accurate genomes. The purpose of the transformation. "It provides us with the possibility of disrupting the strong lycopene β-cyclase function in Dunaliella salina," said Chen Defu.

It is reported that this project will be cooperated by Nankai University and China Salt Salt Engineering Technology Research Institute. At the same time, technological development will transform the existing conditions and technologies into a production workshop with an annual output of 1,000 kilograms of lycopene-rich algae powder. Safe and functional new lycopene product.

This new seaweed is not only suitable for the Tianjin coast natural environment, but also has the advantages of genetic stability, high yield, low cost, safety and health, and simple process. (Zhu Hong, Ping Yang)

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Olympic special vegetables will be on the public table

Special vegetables for the Olympic Village during the Olympic Games will appear on the ordinary citizens' tables in the future. Yesterday, the Municipal Bureau of Commerce and the Municipal Agricultural Committee jointly organized a negotiation and matchmaking activity between five Olympic vegetable processing companies and the city’s large-scale supermarket chains and catering companies, which prompted several cooperation intentions on the spot.

Participated in the joint ventures such as Shunxin Innovation, Yunong, Kangyipin, Grand Canal and the creation of five vegetable cutting companies. During the Olympic Games, they shouldered all the tasks of providing cutting vegetables to the Olympic Village and supplied more than 120 tons of Olympic special vegetables. . The products produced by these companies mainly include vacuum-packed dishes, semi-finished products that can be directly cooked, and salad-like ready-to-eat products. Corporate officials said that most of the products have never been supplied to the market.

Wal-Mart, Carrefour, Wumart, Supermarket, Jingkelong and other retail companies and catering companies such as Cheap Place, Quanjude, and Leopard held talks with the five special vegetable suppliers for the Olympic Games. Several preliminary sales intentions were reached on the spot.

The person in charge of the Grand Canal Agricultural Product Distribution Center stated that the special vegetables for the Olympic Games were imported from designated bases in a country-specific manner, and the prices of processed products were about 20% to 30% higher than ordinary pollution-free green foods. The supply of products is very sufficient, and the goods can be delivered soon after the agreement is reached. In the fastest two or three days, they can appear on supermarket shelves. (Reporter Gu Xiaoyu)

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